Hemoglobin aptamer
Web15 jun. 2015 · This measuring system used nucleic-acid aptamers that exhibited high sensitivity and high specificity for hemoglobin and HbA1c to perform a stable and robust testing. The compact microfluidic system consumed less samples and reagents and significantly shortened the detection time.
Hemoglobin aptamer
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Web15 jun. 2015 · In this work, an integrated microfluidic system using aptamer-based testing to measure HbA1c in blood samples is therefore presented. This measuring system used nucleic-acid aptamers that exhibited high sensitivity and high specificity for hemoglobin and HbA1c to perform a stable and robust testing. WebAptamer Chemistry: DNA Target: Hemoglobin Antigen/Target Category: Protein Affinity (Kd): 7.6 nM (reported value) Binding Conditions/Buffer: Aptamer binding took place in human blood sample produced by centrifuging 100 µL of whole human blood, collecting the pellet of red blood cells, resuspending the pellet in 50 µL of deionized water, and …
Web15 mei 2016 · On-chip, aptamer-based sandwich assay for detection of glycated hemoglobins via magnetic beads Diabetes can be diagnosed and monitored by measurement of the cutoff ratio between glycated hemoglobins (HbA1c) and total hemoglobin (Hb), which does not require a fasting blood sample and is less influenced … WebThiol modified aptamer oligonucleotide with gold nanoparticles ([email protected]) were synthesized for colorimetric detection of glycated hemoglobin (HbA1c) in …
Web15 dec. 2024 · We established an aptamer-based colorimetric detection of human hemoglobin in microplates and demonstrated that quadruplex-forming 2′-F-RNA … Web2 apr. 2024 · Aptamers are oligonucleotides that bind with high affinity to target molecules of interest. One such target is glycated hemoglobin (gHb), a biomarker for assessing glycemic control and diabetes ...
WebThe obtained aptamer has no toxicity and small molecular weight, can be synthesized and marked easily, specifically identifies glycosylated hemoglobin (GHb), does not identify or combine other homologous non-glycosylated hemoglobin (Hb), and can be used as a molecular beacon for detecting the content of glycosylated hemoglobin (GHb).
Web21 apr. 2024 · Aptamers are short single stranded DNA (ssDNA) or RNA sequences that have been recently appeared 15 as novel recognition receptors which can be used as alternative to antibodies in biosensing devices. Aptamers can be selected in vitro against a variety of targets including small molecules, metal ions and proteins using a process … medchessWeb12 apr. 2024 · This method exhibited significant selectivity against target among ten coexisting proteins (fibrinogen, hemoglobin, cytochrome C, serum albumin, alkaline phosphatase, T4 polynucleotide kinase in blood serum, and amylase, sialomucin, lysozyme, and immunoglobulin G usually discovered in saliva), attributed to the highly selective … penang undersea tunnel feasibility study costWeb15 jan. 2024 · Glycated hemoglobin (HbA1c) has been widely explored as an important marker for monitoring and diagnosing diabetes. Due to the advantages of high … penang weather forecast 14 daysWeb15 mei 2016 · On-chip, aptamer-based sandwich assay for detection of glycated hemoglobins via magnetic beads Diabetes can be diagnosed and monitored by … penang townWeb15 aug. 2024 · Binding of nucleic acid aptamers to specific targets and detection with fluorescence anisotropy (FA) or fluorescence polarization (FP) take advantage of the complementary features of aptamers and the fluorescence techniques. We review recent advances in affinity binding assays using aptamers and FA/ … medchest pharmacyWebBiotin Modified Anti-Hemoglobin Aptamer (CAT#: CTApt-M-1619) For Research Use Only. Not for Diagnostic or Therapeutic Applications. Name. * Phone. * Email. * Products or … penang version ice kachangWeb20 apr. 2024 · Aptamers are oligonucleotides that bind with high affinity to target molecules of interest. One such target is glycated hemoglobin (gHb), a biomarker for assessing … medchest return