Genetic modularity

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August undefined, 2024

WebNational Center for Biotechnology Information WebAug 1, 2015 · Definitions of “modularity” vary widely; nevertheless, implicit assumptions of modular organization are central both to studies of developmental mechanisms, and to evolutionary analyses of morphology, physiology, and phylogeny. ... carefully defining developmental units or modules is a key first step in the pursuit of underlying genetic ...

A systems-biology approach to modular genetic complexity

WebMay 22, 2015 · The ortholog-function conjecture posits that orthologous genes in diverged species perform similar or identical functions ().The conjecture is supported by … WebModularity in RNA molecules is “the partitioning of RNA molecules into subunits that are simultaneously independent with respect to their … thinning yacht varnish

Modularity in Development and Why It Matters to Evo-Devo1

Modularity refers to the ability of a system to organize discrete, individual units that can overall increase the efficiency of network activity and, in a biological sense, facilitates selective forces upon the network. Modularity is observed in all model systems, and can be studied at nearly every scale of … See more The exact evolutionary origins of biological modularity has been debated since the 1990s. In the mid 1990s, Günter Wagner argued that modularity could have arisen and been maintained through the interaction of four … See more • SF Gilbert, JM Opitz, and RA Raff. 1996. "Resynthesizing Evolutionary and Developmental Biology". Developmental Biology. 173:357-372 See more • W Bateson. Materials for the Study of Variation. London:Macmillan, 1984. • R Raff. The Shape of Life. University of Chicago Press, 1996. See more WebJun 8, 2012 · Hierarchical Modularity of Genetic Interactions Previous work has shown that the genetic interactions between genes encoding components of the same protein … WebDevelopmental modularity, i.e., coherent organization and function of developmentally related traits, is an emergent property of organismic development and evolution. However, knowledge about how modular variation and evolution are driven genetically is still limited. Here, using ornamental plants as an example, we propose a computational framework to … thinning watermelon seedlings

A systems-biology approach to modular genetic complexity

Sex, mixability, and modularity PNAS

WebJun 6, 2024 · Structural modularity is widely regarded as a necessary condition for the evolvability of complex networks. ‘Evolvability,’ in the general sense of the term, is … WebMay 22, 2015 · This modularity of gene replacement suggests that ancestral essential genes are critically retained in pathway-specific manner and resilient to drift in sequence, … thinning women\u0027s hair treatmentWebDec 2, 2016 · that if genetic drift is the only operating evolutionary process, modularity patterns would not be stable and patterns of association would vary widely across closely … thinning women hair

"WebJan 17, 2024 · Genetic modularity refers to patterns of joint effects between genes on traits that can be represented as a network of relationships between pleiotropic traits 26. " - Genetic modularity

Genetic modularity

National Center for Biotechnology Information

WebSep 20, 2009 · Thus, a connection was hypothesized between sex, separate contributions to fitness, and genetic modularity ( 2, 5 ), the last of which has become widely appreciated for its importance to evolution as … WebApr 12, 2024 · Pollinator-mediated selection is supposed to influence floral integration. However, the potential pathway through which pollinators drive floral integration needs further investigations. We propose that pollinator proboscis length may play a key role in the evolution of floral integration. We first assessed the divergence of floral traits in 11 …

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WebJul 15, 2014 · Introduction Morphological integration and modularity depend on genetic covariation between traits, which emerges from pleiotropic effects of single loci and genetic linkage between loci. Since chromosomal reorganizations alter meiotic recombination, they might modify groups of linked genes and entail the fixation of new alleles with new … WebAug 19, 2014 · The genetic component of integration and modularity is important because it is a crucial determinant of the potential for evolutionary change in a structure. Genetic integration between parts means that selection on one part will produce a correlated response in other parts, whereas genetic modularity can facilitate independent …

Webregions or genetic networks is directly advanced by selective mechanisms. However, the processes of duplication, degenerative mutation, and random genetic drift can lead to the passive emergence of modularity in populations of with genetic effective sizes of the magnitude found in multicellular species. 9. Natural selection promotes the ability ...

WebMay 1, 2014 · modular genetics. Modular Genetics, Inc. (Modular) uses its proprietary automated gene engineering system to create new products. Modular's unique … WebJul 23, 2008 · Similar disease phenotypes are engendered as a result of the modular nature of gene networks; thus we hypothesized that all human genetic disease phenotypes …

WebEvolutionary developmental biology focuses on understanding the origin and evolution of extant biological variation, and the genetic basis for this variation. The genetic toolkit appears largely finite across animals, such that a combination of regulatory evolution, gene recruitment (co-option) and genetic modularity often allow morphological and …

WebDec 14, 2001 · Figure 1 Synthetic genetic array methodology (). (i) A MATα strain carrying a query mutation (bni1Δ) linked to a dominant selectable marker, such as the nourseothricin-resistance marker natMX that confers resistance to the antibiotic nourseothricin, and anMFA1pr-HIS3 reporter is crossed to an ordered array ofMAT a viable yeast deletion … thinning woodland managementWebModularity is probably caused by multiple forces acting tovarious degrees in different contexts [4], and a comprehensive understanding of the evolutionary ... (§4), such as a … thinning wipe on polyWebModularity has emerged as a central concept for evolutionary biology, thereby providing the field with a theory of organismal structure and variation. This theory has reframed long-standing questions and serves as a unified conceptual framework for genetics, developmental biology, and multivariate evolution. Research programs in systems … thinning your book shelvesWebGenetic and functional modularity of Hox activities in the specification of limb-innervating motor neurons. PLOS Genetics January 24, 2013 Other authors thinning woodlands ukWebModularity refers to the ability of a system to organize discrete, individual units that can overall increase the efficiency of network activity and, in a biological sense, facilitates selective forces upon the network. Modularity is observed in all model systems, and can be studied at nearly every scale of biological organization, from molecular interactions all … thinning wood stainWebMar 1, 2013 · MAs are named differently such as genetic local searchers and Lamarckian genetic algorithms. An MA for community detection [32] has been proposed to optimize … thinning your hair pros and consWebNov 3, 2010 · Another possible benefit of modularity may arise from the simple combinatorial aspect of genetic variation within a large genome. Twenty-six genes … thinning woods